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Postdoctoral Research Fellowship in Medical Device Materials Engineering

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

A Postdoctoral research fellowship in the area of materials engineering for medical imaging/sensing devices is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. The research fellow will be co-advised by Prof. Jennifer A. Lewis at the School of Engineering and Applied Sciences, Harvard University. This appointment will be made at the rank of postdoctoral fellow at Harvard Medical School. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new medical diagnostic techniques with applications in basic and clinical research.

The fellowship will focus on development and optimizing polymer material for medical sensing and imaging devices and related technologies. The specific aim of the fellowship can be tailored to meet individual goals, which will provide an opportunity to build clinical, research, and publication experience.

Clinical applications of these technologies include diagnosis of gastrointestinal and pulmonary diseases and diagnosis of coronary atherosclerosis. Representative recent publications from the lab include:

Gastrointestinal Endoscopy 2008; 68:745-53
JACC Cardiovascular Imaging 2008; 1:752-61
Nature Medicine 2009;15:1219-23
Nature Medicine 2011; 17:1010-4
Nature Medicine 2011; 17:1680-4.
Nature Medicine 2013; 19:238-41

Requirements:
A PhD (or equivalent) in Biomedical Engineering, Materials Engineering, Chemical Engineering, Polymer Chemistry or a related field is required. Demonstrated excellence in polymer synthesis, characterization, and optimization is required. Additionally, expertise in one or more of the following areas is desired: product stability, material biocompatibility, clinical studies with novel devices. Creativity is highly desirable.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest, and contact information for three letters of reference. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.

Senior Program Manager for Device Development

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

 

The Tearney Laboratory (www.tearneylab.org) at the Wellman Center at Massachusetts General Hospital comprises one primary faculty and approximately forty undergraduate, graduate and post-doctoral (MD/PhD) trainees. Dr. Tearney is a Principal Investigator of federal and non-federal research funding with an extensive research program in the development and clinical application of novel optical medical imaging technologies for disease diagnosis and therapy guidance. The Tearney Laboratory is dedicated to advanced innovative medical imaging device development from research to proof-of-concept human studies and to multi center clinical trials. The regulatory program in the Tearney Laboratory oversees the development and translation process, implements documentation and quality controls and is responsible for all regulatory filings with FDA and IRB.

Role description
The Senior Program Manager will be responsible for directing the regulatory activities for the Tearney Laboratory.
The Senior Program Manager will also act as a professional advisor to Dr. Tearney on all aspects of the Tearney Laboratory activities and assist Dr. Tearney in developing a vision and strategic plan to guide the growth of the laboratory.

Program planning and management
In collaboration with Dr Tearney, plan and coordinate execution of critical-path project activities for multiple projects, spanning all stages of translation up to early clinical development.
Provide leadership, strategic direction and general management for regulatory programs and services. Ensure excellent working relationships/partnership to consistent quality and standards with all in scope Regulatory Agencies.
In collaboration with project leaders, evaluate strategies, analyze and identify project risks; Effectively identifies issues and challenges and works with project leaders and Dr. Tearney to identify options and implement consensus-based solutions.
Monitor and control the Tearney Laboratory Quality Management System.
Oversee the planning, implementation, execution and evaluation of special projects.
Ensure that all staff are effectively employed and adequately trained to perform their responsibilities and operational tasks in an ethical and responsible manner.

Qualifications
Strong knowledge of the design and execution of scientific projects. Demonstrable experience across the Device Development and commercialization lifecycle, with proven examples of contribution.
Proven ability to manage complex regulatory issues.
Demonstrable experience of effective delivery in a complex matrix environment. Track record of leading and delivering on multiple projects in parallel.
General management experience and previous line management and leadership experience at senior management level is essential.
Proven ability to consistently deliver to time, cost and quality standards.
Unwavering commitment to quality programs and data-driven program evaluation,
At least 10 years of senior management experience; track record of effectively leading and scaling a performance- and outcomes-based organization and staff; ability to point to specific examples of having developed and operationalized strategies that have taken an organization to the next stage of growth.
Strong ability to engage a wide range of stakeholders and cultures. Can be direct and forceful as well as diplomatic. Gains trust quickly of other parties to the negotiations Ability to work effectively in collaboration with diverse groups of people.
Excellence in organizational management with the ability to coach staff, manage, and develop high-performance teams, set and achieve strategic objectives
Strong written and verbal communication skills.
Action-oriented, entrepreneurial, adaptable, and innovative approach to business planning.
Passion, idealism, integrity, positive attitude, mission-driven, and self-directed.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for three letters of reference. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.

 

Device Development Project Manager

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

The Tearney Lab at Massachusetts General Hospital seeks a Project Manager who will play a key role in the administration of the translational research activities of the Tearney Laboratory. The Tearney laboratory is dedicated to advancing innovative medical imaging devices from research to proof-of-concept human studies to multi center clinical trials. The project manager takes overall responsibility for planning and tracking specific project deliverables.

The Project Manager oversees the planning, implementation, and tracking of a specific medical device development and clinical validation project which has a beginning, an end and specified deliverables, works closely with the Principal Investigator to develop a detailed project plan to monitor and track progress. The Project Manager assists in the definition of project scope and objectives, involving all relevant stakeholders and ensuring technical feasibility, ensures resource availability and allocation, coordinates internal resources and third parties/vendors for the flawless execution of projects, manages budget, creates and maintains comprehensive project documentation, and prepares project related reports and supporting documentation for the Principal investigator and funding agencies.

Requirements:
BS/BA Required  MA/MS/MPH Preferred
A minimum of 3 years of experience in project management.
Experience in health care related industry or research academic setting.
Knowledge of clinical studies management, regulatory affairs, or medical drug/device product development a plus.

Must have solid technical background with understanding and/or hands-on experience in medical devices and working experience in project management.  Must be able to function independently and make effective decisions, demonstrate excellent judgment and aptitude in problem solving and have strong organizational, administrative and time management skills. Must have excellent oral and written communication skills as well as interpersonal skills, with ability to interact professionally at all levels, the ability to work both independently and as part of a team is essential. Must have strong database management and computer skills.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for three letters of reference. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.

Postdoctoral Research Fellowships (Optical Coherence Tomography)

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

A Postdoctoral research fellowship in the area of optical coherence tomography (OCT) is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow or instructor at Harvard Medical School, commensurate with the applicant’s experience. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new OCT technologies with applications in basic and clinical research.

The fellowship will focus on high resolution OCT imaging devices, including development of novel optical techniques, engineering of in vivo endoscopic probes, and translation to clinical use. Current medical applications of micro-OCT include imaging of mucociliary clearance to monitor treatment response in pulmonary disorders such as cystic fibrosis, high-resolution imaging of vulnerable plaques in coronary artery disease, and diagnosis of cancer. The ideal candidate for this position is an organized and creative problem-solver experienced with advanced optics, biomedical engineering, computational methods, and image analysis, as well as capable of leading a multidisciplinary research team.

Representative recent publications from our group on micro-OCT include:
Nature Medicine 2011; 17:1010-4
PLOSONE 2013; 8:e54473
Am J Respir Crit Care Med 2014; 190:421-32
Am J Respir Cell Mol Biol 2014; 51:485-93

Requirements:
A PhD (or equivalent) in Biomedical Engineering, Electrical Engineering, Physics or a related field is required. Demonstrated excellence in one or more of the following areas is required: optical coherence tomography, optical imaging systems, optical design, optical system fabrication, fiber optic systems and components, broadband light source development, spectroscopy, image processing and programming in Visual C++, clinical studies with novel devices. Creativity is highly desirable.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for three letters of reference. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.

Postdoctoral Research Fellowship in
In Vivo Microscopy

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

A Postdoctoral research fellowship in the area of In Vivo Microscopy is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow at Harvard Medical School. MGH’s role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new in vivo microscopy technologies with applications in basic and clinical research.

The fellowship will focus on the development and clinical application of advanced in vivo microscopy imaging devices, including endoscopic OCT, multimodality OCT, high-resolution OCT, spectroscopic OCT, FFOCM, confocal microscopy, SECM, capsule endomicroscopy, oblique-backscattering microscopy (OBM), and related technologies. The specific aim of the fellowship can be tailored to meet individual goals, which will provide an opportunity to build clinical, research, and publication experience.

Clinical applications of these technologies include diagnosis of cancer in the gastrointestinal and pulmonary tracts, and diagnosis of atherosclerosis in the cardiovascular system. Representative recent publications from the lab include:
Gastrointestinal Endoscopy 2008; 68:745-53
JACC Cardiovascular Imaging 2008; 1:752-61
Nature Medicine 2009;15:1219-23
Nature Medicine 2011; 17:1010-4
Nature Medicine 2011; 17:1680-4.
Nature Medicine 2013; 19:238-41

Requirements:
A PhD (or equivalent) in Biomedical Engineering, Electrical Engineering, Physics or a related field is required. Demonstrated excellence in one of the various forms of optical coherence tomography, confocal microscopy, or other in vivo microscopy techniques is required. Additionally, expertise in one or more of the following areas is desired: optical imaging systems, optical design, circuit design, optical system fabrication, fiber optic systems and components, broadband light source development, spectroscopy, image processing, programming in C++, clinical studies with novel devices. Creativity is highly desirable.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for three letters of reference.. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.

Research Engineer in Biomedical Optics

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

The Tearney Laboratory in the Wellman Center for Photomedicine at Massachusetts General Hospital invites applications for the position of research engineer. The Laboratory is focused on the development and clinical validation of non-invasive, high-resolution optical imaging methods for disease diagnosis. Representative imaging technologies include optical coherence tomography, confocal microscopy, autofluorescence, near infrared and Raman spectroscopy.

The primary responsibility of the research engineer is to work within a multidisciplinary team of research scientists, engineers and clinicians focused on the development of innovative biomedical optical imaging devices to be implemented in new or ongoing research and clinical studies. The research engineer will design, develop, fabricate and test integrated hardware, software systems, imaging and medical devices. In addition, the engineer will be responsible for generating complete system documentation and developing QA/QC standards. He/she will also train medical and other technical staff in the safe and proper use of the clinical system and devices. Working as a member of the research team, the engineer may also participate in the development of preclinical systems and devices.

Clinical applications of these technologies include diagnosis of cancer in the gastrointestinal and pulmonary tracts, and diagnosis of atherosclerosis in the cardiovascular system. Representative recent publications from the lab include:

  • Gastrointestinal Endoscopy 2008; 68:745-53
  • JACC Cardiovascular Imaging 2008; 1:752-61
  • Nature Medicine 2009;15:1219-23
  • Nature Medicine 2011; 17:1010-4
  • Nature Medicine 2011; 17:1680-4.
  • Nature Medicine 2013; 19:238-41

Requirements:
A BS degree in biomedical engineering, physics, mechanical engineering, electrical engineering, or related field is required. The ideal candidate has demonstrated medical engineering experience with a strong background in electronics, optical system fabrication, data acquisition, instrument control, and fiber optics. Individuals with research or commercial experience from a hospital, industrial, or academic setting are encouraged to apply. Proficiency in SolidWorks, Matlab, Labview, Visual C++ and ImageJ is a plus.

Contact:
Interested candidates are encouraged send a CV accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for three letters of reference.. Address correspondence to Dr. Gary Tearney, note the position you are applying for in the subject line, and send by email to Crystal Spencer at: tearneylabsearch@partners.org. MGH is an equal opportunity employer.


Research Technician 1

The Tearney Lab
Wellman Center for Photomedicine
Massachusetts General Hospital
Boston, MA USA

The Tearney Laboratory at the Massachusetts General Hospital is a multidisciplinary research laboratory that invents, designs and validates innovative optical diagnostic imaging technologies in clinical studies. The Tearney lab develops microscopy catheters in house and uses them to diagnose various diseases including those in the GI tract and the heart. Ultimately the focus of our lab is to conduct microscopy of entire human body in vivo. The clinical manufacturing and regulatory team is key to the translation of our technologies from bench to bedside. A critical member to this team, the research technician, assembles and tests imaging catheters used in clinical research.

The Research Technician will be responsible for assembling complex imaging catheters for multiple clinical applications. The assembly of all components and sub-assemblies will be performed using drawings, bills of materials, and written instructions. Fabrication work will involve precise polishing and alignment of optical components. The Research Technician will also be responsible for testing and troubleshooting all sub-assemblies and final assemblies. The Research Technician will also conduct in-process quality checks to ensure that established quality standards are met.

Duties and Responsibilities:

  • Assemble catheters for various clinical applications based on drawings and written instructions.
  • Work from and understand schematics, diagrams, written and verbal instructions
  • Align and assemble small components
  • Assemble mechanical systems
  • Testing and troubleshooting of sub-assemblies and final assemblies
  • Conduct in-process quality checks to ensure the established quality standards
  • Feedback and support engineering activities such as design, test, checkout and modification

Desired Skills, Experience & Qualifications:

  • High school diploma or GED equivalent, Associates Degree a plus
  • Proficient with computers, internet, Microsoft word, Powerpoint, Excel, & Outlook
  • 2-5 years of optics or mechanical assembly experience
  • Skilled in using hand tools and basic electronic and mechanical equipment
  • Have the ability to read and follow assemble drawings and directions
  • Good organization skills and the ability to function with minimal supervision

Contact:
Interested candidates are encouraged send a resume accompanied by a cover letter describing any previous research training, specific areas of interest and contact information for two letters of reference. Address correspondence by email to Dr. Gary Tearney and send to Crystal Spencer at: tearneylabsearch@partners.org MGH is an equal opportunity employer.