Professor Tearney

Prof. Tearney’s research interests are focused on the development and clinical validation of non-invasive, high-resolution optical imaging methods for disease diagnosis.


Education

Guillermo (Gary) Tearney M.D., Ph.D. is a Mike and Sue Hazard Family MGH Research Scholar, Professor of Pathology at Harvard Medical School, an Affiliated Faculty member of the Harvard-MIT Division of Health Sciences and Technology (HST), and maintains his lab at the Wellman Center for Photomedicine at the Massachusetts General Hospital. Prof. Tearney received his MD magna cum laude from Harvard Medical School and received his PhD in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology.

Research Interests

Prof. Tearney’s research interests are focused on the development and clinical validation of non-invasive, high-resolution optical imaging methods for disease diagnosis. Prof. Tearney’s lab was the first to perform human imaging in the coronary arteries and gastrointestinal tract in vivo with Optical Coherence Tomography (OCT), which provides cross-sectional images of tissue architectural microstructure at a resolution of 10 µm. He has also conducted many of the seminal studies validating OCT and is considered an expert on OCT image interpretation. Recently, Prof. Tearney’s lab has invented a next generation OCT technology, termed µOCT, which has a resolution of 1 µm and is capable of imaging cells and sub cellular structures in the coronary wall.

Prof. Tearney has also developed several other technologies, including a confocal endomicroscope capable of imaging the entire esophagus, an ultraminiature three-dimensional endoscope, a highly efficient form of near field scanning optical microscopy (NSOM), and novel fluorescence spectroscopy and multimodality imaging techniques. He has an active program in Raman spectroscopy and has conducted the first intracoronary Raman in vivo. Prof. Tearney is co-editor of The Handbook of Optical Coherence Tomography and has written over 170 peer-reviewed publications, including papers that have been highlighted on the covers of Science, Nature Medicine, Circulation, Gastroenterology, and Journal of American College of Cardiology.

Prof. Tearney has over 400 patent applications (~100 granted) and licenses on more than 200 patents/applications resulting in commercial medical devices. In addition, Dr. Tearney has served as principal investigator on over 40 grants, including NIH R01’s from the NCI, NIBIB, NHLBI, and NIDDK.

Prof. Tearney’s work extends beyond his laboratory at MGH, many of his technologies are being produced commercially, he is a member of the Scientific Advisory Board for; Massachusetts Life Sciences Center, the Clinical Advisory Board for; NinePoint Medical and he has founded the International Working Group on Intracoronary OCT Standardization and Validation, a group that is dedicated to establishing standards to ensure the widespread adoption of this imaging technology.

 Gary Tearney CV